- Yojimbo (film), a 1961 jidaigeki film by Akira Kurosawa, starring Toshiro Mifune
- Kaze no Yojimbo, 2001/2002 animated television program based on the Kurosawa film
- Usagi Yojimbo ("Rabbit Bodyguard"), a 1984 comic book series created by Stan Sakai
- Yojimbo (software), an information organizer for Mac OS X, by Bare Bones Software, released in 2008
- Zatoichi Meets Yojimbo, a 1970 film, directed by Kihachi Okamoto
- Yo-Jin-Bo, a visual novel about three yojinbo. Initially published in Japanese in 2005, then released in English by Hirameki International in 2006
- Yojimbo, a secret Aeon found in the video game Final Fantasy X
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