Little performed in The Groundlings in Los Angeles. Joe Murray encountered Little and asked Little if he was interested in being a voice actor and decided that Little matched the "Dung Bettle" characters Chip and Skip.
He made an appearance in the movie Accepted. He has made three appearances as "Crazed Naked Man" on Reno 911! Steve has voiced Chip & Skip and Lemmings on Camp Lazlo and worked as a writer for the show; his writing partner was usually Merriwether Williams. In August 2010 he appeared on the MTV comedy series Warren the Ape.
Little is currently playing the recurring character Stevie Janowski, a band teacher who idolizes and serves as the personal assistant of the main character, Kenny Powers, on the HBO series Eastbound & Down.
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