Rachael Ann MacFarlane (born March 21, 1976, in Kent, Connecticut) is an American voice actress best known for her appearances in the FOX animated series Family Guy and American Dad!, both created and executive-produced by her older brother Seth MacFarlane.
Aside from voice acting, MacFarlane has also been involved in other aspects of animation, such as being a production manager for Billy and Mandy and Welcome to Eltingville. She also wrote an episode of Billy and Mandy, titled "Educating Grim".
Among Rachael MacFarlane's best known voice roles are:
- The Grim Adventures of Billy and Mandy - Mindy and Eris, the Goddess of Discord and Chaos
- American Dad! - Hayley Smith
- Codename: Kids Next Door - Supreme Leader Numbuh 362
- Family Guy - Olivia Fuller, Meg Griffin (pilot) and various characters
- Static Shock - Nina Crocker/Time-Zone
- The Batman - Blaze
- StarCraft II: Wings of Liberty (video game) - Kate Lockwell (UNN reporter)